January 22nd, 2015
Are you aware that malignancy of urinary bladder claimed approximately 16,000 lives in the year 2014? This corresponds to approximately 2.5% of all cancer related deaths in the United States (1). Bladder malignancy is the result of abnormal growth and metabolism of transitional cells within the lining of urinary bladder. It has been estimated that approximately 75,000 new cases of bladder cancer were diagnosed in the year 2014 (which comprises of 4.5% of all the new cancer that were diagnosed in that year). Fortunately, due to advancements in the field of science and technology, the mortality rate due to bladder cancer is fairly low in United States; however, the malignancy itself affects the quality of life by interfering with the health and overall wellness.
Due to chronic exposure to toxins and environmental irritants, the risk of malignant transformation of cells increases significantly. Following are some risk factors that may further aggravate your risk of developing bladder malignancy.
Bladder cancer can be prevented by incorporating healthy lifestyle changes. For example:
Fresh vegetables are very beneficial for the maintenance of optimal health. Fresh organic vegetables are rich in high quality fiber and naturally occurring flavonoids, antioxidants and pigments that are known to ward off free radicals and minimize the risk of malignancy.
According to a new study reported in the peer reviewed British Journal of Cancer (4), investigators suggested that Vitamin B1 and other micronutrients (that are richly supplied by organic vegetables) are protective against bladder cancer and other types of malignant lesions. Study also suggested that individual who consume large amounts of processed meat are at much higher risk of developing bladder cancer (4)
Exposure to irritants or chemicals (such as industrial wastes or insecticides and pesticides) are known to cause bladder malignancy. For best results, it is highly recommended to limit the exposure to chemicals by relying on organic dietary sources. Additionally, develop a habit of properly washing your fruits/ veggies before consumption.
Impaired immune defenses due to chronic metabolic or medical illnesses can significantly increase the risk of malignant transformation of cells. Latest research indicates that chronic, uncontrolled diabetes can significantly aggravates the risk of bladder malignancy and other cancer. More importantly, certain hypoglycemic drugs like pioglitazone are very strongly associated with an aggravated risk of bladder cancer, according to a new study reported in Diabetes Care (5).
It is imperative to understand that a great degree of care and caution is needed while using supplements or micronutrient agents like selenium for the prevention of bladder cancer. Experts believe that the maximum effective dose of selenium is 150-300 mcg/ day. Exceeding this dose can increase the risk of systemic dysfunction and may aggravate the risk of developing diabetes.
Likewise, other antioxidants and nutritional supplements like Vitamin E and C are also advised to minimize the risk of recurrence of bladder and other cancers. Extensive clinical and laboratory research indicates that Vitamin E supplementation can inhibit the abnormal migration of cancerous cells.
Other preventive tips are:
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